⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292897 | 0.87 | — | — | |
| SCHEMBL10582005 | 0.83 | — | — | |
| SCHEMBL9723624 | 0.81 | — | — | |
| SCHEMBL9230585 | 0.78 | — | — | |
| SCHEMBL9181723 | 0.77 | — | — | |
| SCHEMBL9181729 | 0.77 | — | — | |
| SCHEMBL9182211 | 0.76 | — | — | |
| SCHEMBL9182217 | 0.76 | — | — | |
| SCHEMBL6681633 | 0.74 | — | — | |
| SCHEMBL9181037 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731148-B2 | High optical quality molds for use in contact lens production | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-20100048636-A1 | Aspartic Protease Inhibitors | VITAE PHARMACEUTICALS, INC. | 2010-02-25 | — | — | US | disclosed |
| US-20090020683-A1 | High optical quality molds for use in contact lens production | JOHNSON & JOHNSON VISION CARE, INC. | 2009-01-22 | — | — | US | disclosed |
| US-7422710-B2 | Method for manufacturing a contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-09-09 | — | — | US | disclosed |
| EP-1368180-B1 | HIGH OPTICAL QUALITY MOLDS FOR USE IN CONTACT LENS PRODUCTION | JOHNSON & JOHNSON VISION CARE (US) | 2007-02-07 | — | — | EP | disclosed |
| US-20050167864-A1 | Method for manufacturing a contact lens | TURNER DAVID C (US) | 2005-08-04 | — | — | US | disclosed |
| US-6861123-B2 | Silicone hydrogel contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2005-03-01 | — | — | US | disclosed |
| EP-1368180-A2 | HIGH OPTICAL QUALITY MOLDS FOR USE IN CONTACT LENS PRODUCTION | Johnson & Johnson Vision Care, Inc. (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002083400-A2 | HIGH OPTICAL QUALITY MOLDS FOR USE IN CONTACT LENS PRODUCTION | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| US-20020099112-A1 | High optical quality molds for use in contact lens production | JOHNSON & JOHNSON VISION CARE, INC. | 2002-07-25 | — | — | US | disclosed |