⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498091 | 0.80 | — | — | |
| SCHEMBL29307213 | 0.78 | — | — | |
| SCHEMBL10053872 | 0.78 | HSD17B10 (0.31) | — | |
| SCHEMBL9408165 | 0.76 | — | — | |
| SCHEMBL15827457 | 0.76 | — | — | |
| SCHEMBL11000960 | 0.73 | — | — | |
| SCHEMBL24762876 | 0.72 | — | — | |
| SCHEMBL10993747 | 0.70 | — | — | |
| SCHEMBL19682781 | 0.70 | — | — | |
| SCHEMBL5976602 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277342-A1 | METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES | MCGEE JOSEPH A (US) | 2012-11-01 | — | — | US | disclosed |
| US-8246168-B2 | Methacrylate-based bulky side-chain siloxane cross linkers for optical medical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-08-21 | — | — | US | disclosed |
| US-20100118261-A1 | METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES | VRX HOLDCO LLC | 2010-05-13 | — | — | US | disclosed |