Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795980 | 1.00 | MEN1 (0.51) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL7206193 | 0.76 | CHRM3 (0.57) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL827869 | 0.76 | CHRM3 (0.57) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3980371 | 0.76 | CHRM3 (0.57) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27751858 | 0.74 | MEN1 (0.68) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL7525984 | 0.74 | CHRM3 (0.45) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6828946 | 0.73 | MEN1 (0.54) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL10813833 | 0.73 | CHRM3 (0.42) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27751859 | 0.72 | MEN1 (0.64) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL5857109 | 0.72 | CHRM3 (0.38) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087291-A1 | 3-CARBOXY-4-(R)-PHENYLPYRROLYDINE-2-ONE SALT AND ITS USE | JSC OLAINFARM (LV) | 2015-06-18 | — | — | WO | claimed |
| US-20240103013-A1 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF | VIB VZW (BE) | 2024-03-28 | — | — | US | disclosed |
| EP-4273549-A1 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF | VIB VZW (BE) | 2023-11-08 | — | — | EP | disclosed |
| EP-3557254-B1 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF | VIB VZW (BE) | 2021-12-15 | — | — | EP | disclosed |
| EP-3557255-B1 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF | VIB VZW (BE) | 2021-11-17 | — | — | EP | disclosed |
| US-11162954-B2 | Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof | VIB VZW (BE) | 2021-11-02 | — | — | US | disclosed |
| US-11162953-B2 | Protein binding domains stabilizing functional conformational states of GPCRS and uses thereof | VIB VZW (BE) | 2021-11-02 | — | — | US | disclosed |
| EP-2593792-B1 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF | VIB VZW (BE) | 2019-11-13 | — | — | EP | disclosed |
| EP-3557256-A1 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF | VIB vzw (BE) | 2019-10-23 | — | — | EP | disclosed |
| EP-3557255-A1 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF | VIB vzw (BE) | 2019-10-23 | — | — | EP | disclosed |
| EP-0099303-B1 | BENZOTHIOPYRANOPYRIDINONES AND THEIR SALTS, THEIR PREPARATION AND USE AS MEDICAMENTS, AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1987-08-19 | — | — | EP | disclosed |
| US-4567178-A | ANTIULCER AGENTS | DR. KARL THOMAE GMBH (DE) | 1986-01-28 | — | — | US | disclosed |
| US-4550107-A | Condensed diazepinones, their compositions and methods of use as pharmaceuticals | DR. KARL THOMAE GMBH (DE) | 1985-10-29 | — | — | US | disclosed |
| US-4518779-A | 1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines | PENNWALT CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |
| US-4517187-A | 1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants | PENNWALT CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0135125-A2 | NMR imaging utilizing chemical shift reagents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-27 | — | — | EP | disclosed |
| EP-0107825-A1 | 1,3,4,6,7,11b-Hexahydro-7-aryl-2H-pyrazino (2,1-alpha) isoquinolines useful as intermediates and pharmaceutical compounds and methods of preparation | PENNWALT CORPORATION (US) | 1984-05-09 | — | — | EP | disclosed |
| EP-0104604-A1 | 1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation | PENNWALT CORPORATION (US) | 1984-04-04 | — | — | EP | disclosed |
| EP-0099303-A2 | Benzothiopyranopyridinones and their salts, their preparation and use as medicaments, and compositions containing them | ROUSSEL-UCLAF (FR) | 1984-01-25 | — | — | EP | disclosed |
| US-4410527-A | ANTIULCER AGENTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-10-18 | — | — | US | disclosed |