⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891630 | 0.81 | — | — | |
| SCHEMBL12146256 | 0.80 | — | — | |
| SCHEMBL31424550 | 0.80 | — | — | |
| SCHEMBL10661947 | 0.79 | — | — | |
| SCHEMBL237181 | 0.78 | MAPK1 (0.40) | — | |
| SCHEMBL9807363 | 0.77 | — | — | |
| SCHEMBL31370471 | 0.77 | — | — | |
| SCHEMBL14870666 | 0.77 | — | — | |
| SCHEMBL15043228 | 0.73 | — | — | |
| SCHEMBL10717480 | 0.72 | MAPK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103080056-A | Method for preparing hydroxytyrosol by using organic metal compound | LONZA AG | 2013-05-01 | — | — | CN | claimed |
| WO-2012006783-A1 | PROCESS FOR PRODUCTION OF HYDROXYTYROSOL USING ORGANOMETALLIC COMPOUNDS | LONZA LTD (CH) | 2012-01-19 | — | — | WO | claimed |
| CN-117736196-A | Pyridine amide derivative and application thereof | 顺毅股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116348455-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20230019236-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
| WO-2021162493-A1 | PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF | 보로노이 주식회사 | 2021-08-19 | — | — | WO | disclosed |
| WO-2021127499-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-112955438-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2021-06-11 | — | — | CN | disclosed |
| EP-3810580-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Calico Life Sciences LLC (US) | 2021-04-28 | — | — | EP | disclosed |
| US-10954202-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | ABBVIE INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20210009542-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | ABBVIE INC. | 2021-01-14 | — | — | US | disclosed |
| EP-0544792-B1 | NOVEL NUCLEOSIDE ANALOGS | ISIS PHARMACEUTICALS INC (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5677437-A | MACROMOLECULES; REGULATING RNA EXPRESSION; THERAPY | ISIS PHARMACEUTICALS, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1994022886-A1 | HETEROATOMIC OLIGONUCLEOSIDE LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0544792-A4 | NOVEL NUCLEOSIDE ANALOGS | ISIS PHARMACEUTICALS INC (US) | 1994-07-27 | — | — | EP | disclosed |
| US-5223618-A | Automated biosynthesis of oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0544792-A1 | NOVEL NUCLEOSIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003452-A1 | NOVEL NUCLEOSIDE ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 1992-03-05 | — | — | WO | disclosed |
| US-4434032-A | Process for making symmetrical alkanediols and the bis-ethers thereof | BATTELLE DEVELOPMENT CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-3993768-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1976-11-23 | — | — | US | disclosed |