SCHEMBL361374

SCHEMBL361374

CCCCCCCCCc1ccc(Cl)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.73
ESR1 P03372 2/20 0.63
ADRA2A P08913 2/20 0.63
ADORA3 P0DMS8 2/20 0.63
TACR2 P21452 2/20 0.63
SLC6A2 P23975 2/20 0.63
SLC6A4 P31645 2/20 0.63
SLC6A3 Q01959 2/20 0.63
KDM4E B2RXH2 1/20 0.63
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
SHBG P04278 1/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
HSPD1 P10809 1/20 0.63
ADRB3 P13945 1/20 0.63
HTR2C P28335 1/20 0.63
HSPE1 P61604 1/20 0.63
HIF1A Q16665 1/20 0.63
TST Q16762 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27946204 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL5271597 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL28265190 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL3261675 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL5599404 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL811576 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL5834756 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL28816241 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL11959874 1.00 KCNH2 (0.73) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL2056149 0.98 KCNH2 (0.70) KCNH2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1244736-B1 POLYCARBONATE-CONTAINING LIQUID CHEMICAL FORMULATION AND METHODS FOR MAKING AND USING POLYCARBONATE FILM CANDESCENT INTELLECTUAL PROP (US) 2006-12-20 EP claimed
US-6500885-B1 UNIFORM THIN FILMS; SMALL PARALLEL APERTURES THROUGH THE FILM, PARTICULARLY FOR USE IN DEFINING OPENINGS IN THE GATE LAYER OF A GATED ELECTRON EMITTER; SOLUTION WITH SOLVENT CANDESCENT TECHNOLOGIES CORPORATION 2002-12-31 US claimed
EP-4347102-A1 METHOD FOR PRODUCING PHOSGENE BASF SE (DE) 2024-04-10 EP disclosed
CN-103421480-B Surfactant oil displacement composition and method of making the same SINOPEC CORP. (CN) 2015-08-12 CN disclosed
EP-2563818-B1 CASSIA DERIVATIVES LUBRIZOL ADVANCED MAT INC (US) 2014-12-17 EP disclosed
CN-103421480-A Oil displacement surfactant composition and preparation method thereof CHINA PETROLEUM & CHEMICAL 2013-12-04 CN disclosed
US-20130129639-A1 Cassia Derivatives LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-05-23 US disclosed
EP-2563818-A1 CASSIA DERIVATIVES Lubrizol Advanced Materials, Inc. (US) 2013-03-06 EP disclosed
CN-102933607-A Cassia derivatives LUBRIZOL ADVANCED MAT INC 2013-02-13 CN disclosed
EP-2240474-B1 CYCLIC PYRIDYL-N-(1,3,4)-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2012-03-14 EP disclosed
WO-2011137218-A1 CASSIA DERIVATIVES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-11-03 WO disclosed
CN-101454922-A Charge injection layer for electro-optical devices UNI DE VALENCIA ESTUDI GENERA (ES) 2009-06-10 CN disclosed
US-5397447-A Low ionic strength, low energy reactions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1995-03-14 US disclosed
US-5296106-A Dispersing reaction enhancer in fluidic medium, electrifying preactivation mixture to ionic equilibrium, dispersing reactant, electrifying, collecting product THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-03-22 US disclosed
US-5282936-A Using a stable, nonsoluble, porous inorganic nonconductive solid, e.g., a zeolite; low temperature and energy THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-02-01 US disclosed
WO-1993014243-A1 DECOMPOSITION OF HALOGENATED AND POLYHALOGENATED ORGANIC MATERIALS BY ELECTRIFIED MICROHETEROGENEOUS CATALYSIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-07-22 WO disclosed
WO-1993014242-A1 ELECTRIFIED MICROHETEROGENEOUS CATALYSIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-07-22 WO disclosed
EP-0021806-A1 2,3-Dihydro-imidazo (2,1-b) benzothiazole derivatives and pharmaceutical compositions containing them JANSSEN PHARMACEUTICA N.V. (BE) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130129639-A1 Cassia Derivatives MAN1B1, SIGLEC7, MAN2B2 KCNH2 3513/4885ESR1 4202/4885ADRA2A 3658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.