Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 10/20 | 0.71 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL3614460 | 1.00 | PRMT1 (0.71) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL13222308 | 0.99 | PRMT1 (0.70) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL12155000 | 0.99 | PRMT1 (0.70) | PRMT1PRMT5PRMT8BLMMLNR | |
| Iodide SCHEMBL29406318 | 0.95 | PRMT1 (0.69) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL5178572 | 0.94 | PRMT1 (0.68) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL7602492 | 0.94 | PRMT1 (0.68) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL30374836 | 0.94 | PRMT1 (0.68) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL3613405 | 0.91 | PRMT1 (0.64) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL3613407 | 0.91 | PRMT1 (0.64) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL5178551 | 0.90 | PRMT1 (0.62) | PRMT1PRMT5PRMT8BLMMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700264-B2 | Photosensitive resin composition, image forming material and image forming method using thereof | NIPPON PAINT CO., LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20070160935-A1 | Lithographic printing plate material for CTP | NIPPON PAINT CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070099115-A1 | Photosensitive resin composition, image forming material and image forming method using thereof | NIPPON PAINT CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| US-20070059638-A1 | Photosensitive resin composition | NIPPON PAINT CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| US-6899999-B2 | Method of manufacturing composite member, photosensitive composition, porous base material, insulating body and composite member | KABUSHIKI KAISHA TOSHIBA (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030107465-A1 | Passive element component and substrate with built-in passive element | KABUSHIKI KAISHA TOSHIBA (JP) | 2003-06-12 | — | — | US | disclosed |
| US-20030022102-A1 | Method of manufacturing composite member, photosensitive composition, porous base material, insulating body and composite member | KABUSHIKI KAISHA TOSHIBA (JP) | 2003-01-30 | — | — | US | disclosed |