SCHEMBL3615657

SCHEMBL3615657

NC1=CC=C(c2ccc(N)cc2)CC1(S)S

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
TAAR1 Q96RJ0 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3606854 0.98 CYP3A4 (0.36) CYP3A4TDP1ALDH1A1TP53TAAR1
SCHEMBL41543 0.78 CYP3A4 (0.39) CYP3A4TDP1ALDH1A1TP53TAAR1
SCHEMBL844893 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1
SCHEMBL368051 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1
SCHEMBL548251 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1
Hydrochloric Acid SCHEMBL3286109 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1
SCHEMBL2697748 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1
SCHEMBL4613513 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1
Hydrochloric Acid SCHEMBL71899 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1
SCHEMBL7895190 0.77 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54162552-A None JP disclosed
US-7790831-B1 Hyperbranched polybenzazoles via an A3+ B2 polymerization THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2010-09-07 US disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
JP-S54162552-A LIQUID CRYSTAL DISPLAY CELL HITACHI LTD 1979-12-24 JP disclosed