Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782595 | 0.98 | TSHR (0.50) | — | |
| SCHEMBL30350 | 0.98 | — | — | |
| SCHEMBL6250803 | 0.95 | TSHR (0.48) | — | |
| Hydrochloric Acid SCHEMBL27993639 | 0.95 | TSHR (0.48) | — | |
| Fluoride SCHEMBL28479463 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL6052939 | 0.95 | — | — | |
| Sulfuric Acid SCHEMBL29716525 | 0.89 | TSHR (0.44) | — | |
| Thiophene SCHEMBL3260655 | 0.86 | TSHR (0.42) | — | |
| Phenazine SCHEMBL28463043 | 0.84 | CCND3 (0.51) | — | |
| Chloroacetic Acid SCHEMBL10826219 | 0.84 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286181-A1 | PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | US | disclosed |