⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037747 | 0.80 | — | — | |
| SCHEMBL4959422 | 0.75 | — | — | |
| SCHEMBL20394586 | 0.75 | — | — | |
| SCHEMBL6846419 | 0.75 | — | — | |
| Tetrabuthylammonium SCHEMBL8836704 | 0.74 | SLC22A1 (0.44) | — | |
| SCHEMBL4107267 | 0.72 | — | — | |
| SCHEMBL28384976 | 0.71 | — | — | |
| SCHEMBL22588903 | 0.71 | — | — | |
| SCHEMBL8343717 | 0.69 | — | — | |
| SCHEMBL31474846 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150023987-A1 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING | PURDUE RESEARCH FOUNDATION (US) | 2015-01-22 | — | — | US | claimed |
| WO-2012103444-A2 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING | PURDUE RESEARCH FOUNDATION (US) | 2012-08-02 | — | — | WO | claimed |
| US-7718578-B2 | Method of synthesis and testing of combinatorial libraries using microcapsules | MEDICAL RESEARCH COUNCIL (GB) | 2010-05-18 | — | — | US | claimed |
| WO-2007028145-A2 | AGENTS AND METHODS FOR REDUCING PROTEIN TYROSINE PHOSPHATASE 1B ACTIVITY IN THE CENTRAL NERVOUS SYSTEM | DARA BIOSCIENCES, INC. (US) | 2007-03-08 | — | — | WO | claimed |
| EP-4704975-A1 | NOVEL PHOSPHOANTIGEN PRODRUG COMPOUND AND USE THEREOF | University College Cardiff Consultants, Ltd. (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024231319-A1 | NOVEL PHOSPHOANTIGEN PRODRUG COMPOUND AND USE THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2024-11-14 | — | — | WO | disclosed |
| EP-4458412-A1 | NOVEL PHOSPHOANTIGEN PRODRUG COMPOUND AND USE THEREOF | University College Cardiff Consultants, Ltd. (GB) | 2024-11-06 | — | — | EP | disclosed |
| US-11821109-B2 | Compartmentalised combinatorial chemistry by microfluidic control | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230366125-A1 | COMPARTMENTALISED COMBINATORIAL CHEMISTRY BY MICROFLUIDIC CONTROL | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-11-16 | — | — | US | disclosed |
| CN-116529254-A | Phosphonate products and methods | 伊利诺伊大学董事会 | 2023-08-01 | — | — | CN | disclosed |
| US-20200333334-A1 | COMPARTMENTALISED SCREENING BY MICROFLUIDIC CONTROL | MEDICAL RESEARCH COUNCIL (GB) | 2020-10-22 | — | — | US | disclosed |
| US-10705078-B2 | Compartmentalised screening by microfluidic control | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2020-07-07 | — | — | US | disclosed |
| WO-2000014219-A9 | PEPTIDE NUCLEIC ACID-OLIGOADENYLATE CHIMERIC MOLECULES | US GOV HEALTH & HUMAN SERV (US) | 2000-08-10 | — | — | WO | disclosed |
| WO-2000014219-A2 | PEPTIDE NUCLEIC ACID-OLIGOADENYLATE CHIMERIC MOLECULES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5917074-A | Preparation and applications of fluorinated propargyl phosphonate reagents | UNIVERSITY OF MASSACHUSETTS (US) | 1999-06-29 | — | — | US | disclosed |
| WO-1999018138-A1 | PREPARATION AND APPLICATIONS OF FLUORINATED PROPARGYL PHOSPHONATE REAGENTS | UNIVERSITY OF MASSACHUSETTS (US) | 1999-04-15 | — | — | WO | disclosed |
| US-5700786-A | Analogues of adenosine 5'diphosphate and pharmaceutical compositions thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-12-23 | — | — | US | disclosed |
| US-5658890-A | INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-08-19 | — | — | US | disclosed |
| US-5569650-A | C-nucleoside isosters of analogs thereof and pharmaceutical compositions | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-10-29 | — | — | US | disclosed |
| WO-1994029331-A1 | NICOTINAMIDE RIBONUCLEOTIDE ISOSTERS, ISOSTERIC NAD ANALOGUES. THEIR SYNTHESES AND USE IN TREATMENTS OF ALCOHOLISM AND NEOPLASTIC DISEASES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-12-22 | — | — | WO | disclosed |