Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 3/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699140 | 0.84 | DPP4 (0.37) | CPN1CPB2ACE | |
| SCHEMBL5198799 | 0.78 | CPN1 (0.33) | CPN1CPB2ACE | |
| SCHEMBL7446497 | 0.73 | CYP2D6 (0.42) | CPN1CPB2PPARGPPARA | |
| SCHEMBL7441458 | 0.71 | CPN1 (0.47) | CPN1CPB2CYP2C19 | |
| SCHEMBL1919199 | 0.70 | CYP2D6 (0.50) | CPN1CPB2ACE | |
| SCHEMBL3541161 | 0.70 | ACE (0.38) | CPN1CPB2ACECYP2C19 | |
| SCHEMBL23480323 | 0.70 | ACE (0.35) | ACEBRD4 | |
| SCHEMBL1255171 | 0.69 | CYP2D6 (0.56) | ACE | |
| SCHEMBL30222646 | 0.69 | TSHR (0.38) | CPN1CPB2ACEPPARA | |
| SCHEMBL3531187 | 0.69 | KDM4E (0.33) | CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299092-B2 | Derivatives of 2-phenyl-3-hydroxyquinoline-4(1H)-one and methods of their preparation and utilization | UNIVERZITA PALACKEHO (CZ) | 2012-10-30 | — | — | US | disclosed |
| US-20100022587-A1 | DERIVATIVES OF 2-PHENYL-3-HYDROXYQUINOLINE-4(1H)-ONE AND METHODS OF THEIR PREPARATION AND UTILIZATION | UNIVERZITA PALACKEHO (CZ) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022587-A1 | DERIVATIVES OF 2-PHENYL-3-HYDROXYQUINOLINE-4(1H)-ONE AND METHODS OF THEIR PREPARATION AND UTILIZATION | HCCS, CBR3, CYC1 | CPN1 2475/4885CPB2 3577/4885ACE 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.