SCHEMBL3618459

SCHEMBL3618459

CCCCCn1cccc1N

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 19/20 0.50
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PABPC1 P11940 1/20 0.40
APOBEC3A P31941 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9664699 0.78 EEF2K (0.44) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL23046365 0.76
SCHEMBL28235966 0.76 EEF2K (0.46) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL2969786 0.76 TLR8 (0.42) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL30517367 0.76 EEF2K (0.46) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL12301200 0.76 EEF2K (0.46) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL2973033 0.76 TLR8 (0.46) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL18433170 0.76 EEF2K (0.46) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL10764491 0.76 TLR8 (0.43) TLR8NPC1ALDH1A1LMNAPABPC1
SCHEMBL197193 0.74 EEF2K (0.42) TLR8NPC1ALDH1A1LMNAPABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674474-B2 Pesticidal agents on the basis of 1-aryl-aminopyrrol MERIAL LIMITED (US) 2010-03-09 US disclosed