Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187685 | 0.91 | MCHR1 (0.81) | MCHR1KCNH2ALDH1A1TSHR | |
| SCHEMBL6185807 | 0.86 | MCHR1 (0.72) | MCHR1KCNH2ALDH1A1TSHR | |
| SCHEMBL6307274 | 0.86 | MCHR1 (0.75) | MCHR1KCNH2ALDH1A1TSHR | |
| SCHEMBL6188454 | 0.86 | MCHR1 (0.71) | MCHR1KCNH2ALDH1A1TSHR | |
| SCHEMBL6314274 | 0.86 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL6313161 | 0.85 | MCHR1 (0.79) | MCHR1KCNH2ALDH1A1TSHR | |
| SCHEMBL2669488 | 0.85 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL6187989 | 0.84 | MCHR1 (0.77) | MCHR1KCNH2ALDH1A1TSHR | |
| SCHEMBL6205835 | 0.83 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL6308416 | 0.83 | MCHR1 (0.86) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240474-B1 | CYCLIC PYRIDYL-N-(1,3,4)-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-03-14 | — | — | EP | disclosed |
| EP-2183222-B1 | AZOLORAINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF | SANOFI SA (FR) | 2011-08-03 | — | — | EP | disclosed |