Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826997 | 0.89 | PDE4B (0.39) | NR1I2UGCGTSHRMEN1KMT2A | |
| SCHEMBL3619080 | 0.87 | MAPT (0.38) | MAPTGAAALOX12NR1I2UGCG | |
| SCHEMBL1380543 | 0.76 | PDE4B (0.42) | NR1I2UGCGTSHRMEN1KMT2A | |
| SCHEMBL1826996 | 0.76 | PDE4B (0.42) | NR1I2UGCGTSHRMEN1KMT2A | |
| SCHEMBL3561288 | 0.75 | PDE4B (0.41) | NR1I2UGCGTSHRMEN1KMT2A | |
| SCHEMBL1826872 | 0.73 | TNF (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1828096 | 0.73 | TNF (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6843737 | 0.73 | PDE4B (0.45) | TSHRMEN1KMT2A | |
| SCHEMBL3561283 | 0.72 | PDE4B (0.42) | NR1I2UGCGTSHRMEN1KMT2A | |
| SCHEMBL3528755 | 0.71 | PDE4B (0.43) | NR1I2UGCGTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267800-A1 | N-Alkyl-Hydroxamic Acid-Isoindolyl Compounds and Their Pharmaceutical Uses | CELGENE CORPORATION | 2010-10-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267800-A1 | N-Alkyl-Hydroxamic Acid-Isoindolyl Compounds and Their Pharmaceutical Uses | PDE4A, PDE12, PDE4B | MAPT 3511/4885GAA 44/4885ALOX12 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.