Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654183 | 0.90 | PI4KB (0.76) | PI4KBSLC2A1MAPTMAPK1LMNA | |
| SCHEMBL653394 | 0.84 | PI4KB (0.59) | PI4KBMAPTMAPK1LMNAPOLB | |
| SCHEMBL655163 | 0.82 | PI4KB (0.50) | PI4KBMAPTMAPK1LMNAKMT2A | |
| SCHEMBL1720202 | 0.80 | PI4KB (0.55) | PI4KBMAPTMAPK1LMNAPOLB | |
| SCHEMBL654457 | 0.80 | PI4KB (0.77) | PI4KBMAPTMAPK1LMNAPOLB | |
| SCHEMBL654739 | 0.79 | PI4KB (0.83) | PI4KBMAPTMAPK1LMNAPOLB | |
| SCHEMBL656541 | 0.77 | PI4KB (0.81) | PI4KBMAPTMAPK1LMNAPOLB | |
| SCHEMBL1721298 | 0.77 | PI4KB (0.91) | PI4KBMAPTMAPK1LMNAPOLB | |
| SCHEMBL653400 | 0.77 | PI4KB (0.74) | PI4KBMAPTMAPK1LMNAPOLB | |
| SCHEMBL4106516 | 0.76 | PI4KB (0.58) | PI4KBSLC2A1MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103130-A2 | NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2010-09-16 | — | — | WO | claimed |