Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL8111484 | 0.94 | TSHR (0.41) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL4918954 | 0.86 | TSHR (0.42) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL7875149 | 0.85 | TDP1 (0.48) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL1232896 | 0.83 | TSHR (0.48) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL1698005 | 0.83 | TSHR (0.48) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL14524745 | 0.82 | TSHR (0.45) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL10793139 | 0.82 | TRPV1 (0.43) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL10793127 | 0.82 | TRPV1 (0.43) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL10793131 | 0.82 | TRPV1 (0.43) | TSHRTDP1TRPV1CHRM2CHRM4 | |
| SCHEMBL27420071 | 0.81 | TSHR (0.38) | TSHRTDP1TRPV1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290350-A | Heteroaryl and bisheteroaryl derivatives for the treatment of iron death-related disorders | 协同医药发展有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113631535-B | Heteroaryl and bisheteroaryl derivatives for the treatment of iron death-related disorders | 协同医药发展有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-2254935-B1 | COATED POLYOXYMETHYLENES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2235092-B1 | COATED POLYOXYMETHYLENES | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2009098256-A1 | COATED POLYOXYMETHYLENES | BASF SE (DE) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009092698-A1 | COATED POLYOXYMETHYLENES | BASF SE (DE) | 2009-07-30 | — | — | WO | disclosed |