Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289160 | 1.00 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL12073070 | 0.88 | TRPV1 (0.54) | TRPV1 | |
| Hydrochloric Acid SCHEMBL14935625 | 0.86 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL15035158 | 0.86 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL14935719 | 0.80 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL12073818 | 0.80 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL12074361 | 0.80 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL10308062 | 0.80 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL3659950 | 0.80 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL12074400 | 0.78 | TRPV1 (0.39) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142529-A2 | TRPV1 ANTAGONISTS AND USES THEREOF | Purdue Pharma LP (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008132600-A2 | TRPV1 ANTAGONISTS AND USES THEREOF | PURDUE PHARMA L.P. (DE) | 2008-11-06 | — | — | WO | disclosed |