Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13140313 | 0.90 | ADORA2A (0.41) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3620048 | 0.87 | ADORA2A (0.39) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3627241 | 0.87 | ADORA2A (0.39) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3620056 | 0.78 | CYP17A1 (0.37) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3626938 | 0.78 | KDM4E (0.37) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3628999 | 0.78 | KDM4E (0.37) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3622108 | 0.78 | CYP1A2 (0.36) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3618776 | 0.78 | CYP1A2 (0.42) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3622237 | 0.78 | CYP1A2 (0.36) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3626670 | 0.78 | CYP1A2 (0.39) | ADORA2AADORA1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010119879-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010119879-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010119878-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010119878-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |