Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666365 | 0.80 | CYP2A6 (0.40) | CYP2A6KDM4EALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL6294650 | 0.77 | PTPN11 (0.37) | PIM1 | |
| SCHEMBL6293491 | 0.76 | KDM4E (0.37) | CYP2A6PIM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6293492 | 0.76 | CYP2A6 (0.37) | CYP2A6PIM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13322505 | 0.76 | CYP2A6 (0.40) | CYP2A6KDM4EALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL10759266 | 0.76 | CYP2A6 (0.48) | CYP2A6PIM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27954206 | 0.75 | CYP2A6 (0.44) | CYP2A6PIM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28303005 | 0.74 | CYP2A6 (0.47) | CYP2A6PIM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6294610 | 0.74 | KDM4E (0.38) | CYP2A6PIM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30402207 | 0.74 | SYK (0.38) | CYP2A6KDM4EALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050237-A1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-19 | — | — | WO | disclosed |
| WO-2010119878-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |