Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354342 | 0.94 | KDM4E (0.64) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL938755 | 0.94 | KDM4E (0.64) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7821238 | 0.92 | KDM4E (0.62) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29851911 | 0.92 | KDM4E (0.62) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11745797 | 0.91 | KDM4E (0.60) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8083278 | 0.89 | KDM4E (0.50) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| Methoxymethane SCHEMBL29852076 | 0.88 | KDM4E (0.57) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10683475 | 0.87 | KDM4E (0.49) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10686638 | 0.85 | KDM4E (0.48) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8829499 | 0.85 | KDM4E (0.48) | KDM4EFOLH1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103508890-A | Method for preparing 3-(2-oxocyclopentyl)-propionic acid and 3-(2-oxocyclopentyl)-propionic ester | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2014-01-15 | — | — | CN | claimed |
| CN-111253246-B | Acyl acid derivative and preparation method and medical application thereof | 中国医学科学院基础医学研究所 | 2023-03-17 | — | — | CN | disclosed |
| WO-2022207923-A1 | SUBSTITUTED LACTONES, POLYMERS THEREOF, AND PROCESSES FOR PREPARING SAME | SCE FRANCE (FR) | 2022-10-06 | — | — | WO | disclosed |
| CN-111253246-A | Acyl acid derivative and preparation method and medical application thereof | 中国医学科学院基础医学研究所 | 2020-06-09 | — | — | CN | disclosed |
| CN-109824500-A | A kind of preparation method and application of 2- benzylimidazoline and Pyromellitic Acid anhydride adduct | 阜阳市诗雅涤新材料科技有限公司 | 2019-05-31 | — | — | CN | disclosed |
| EP-2598479-B1 | A METHOD FOR PREPARING RAMIPRIL | AARTI HEALTHCARE LTD (IN) | 2015-04-01 | — | — | EP | disclosed |
| CN-103282350-B | Process for the preparation of ramipril | AARTI HEALTHCARE LTD | 2015-02-04 | — | — | CN | disclosed |
| CN-103508890-A | Method for preparing 3-(2-oxocyclopentyl)-propionic acid and 3-(2-oxocyclopentyl)-propionic ester | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-103508890-A | Method for preparing 3-(2-oxocyclopentyl)-propionic acid and 3-(2-oxocyclopentyl)-propionic ester | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-103508890-A | Method for preparing 3-(2-oxocyclopentyl)-propionic acid and 3-(2-oxocyclopentyl)-propionic ester | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2014-01-15 | — | — | CN | disclosed |
| US-5567844-A | Process for preparing 1-phenyl-2-amino-3-fluoro-1-propanols | ZAMBON S.P.A. (IT) | 1996-10-22 | — | — | US | disclosed |
| EP-0130633-B1 | Process for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives | ZAMBON SPA (IT) | 1996-10-09 | — | — | EP | disclosed |
| EP-0678506-A2 | Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives | ZAMBON GROUP S.p.A. (IT) | 1995-10-25 | — | — | EP | disclosed |
| EP-0677511-A2 | Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives | ZAMBON GROUP S.p.A. (IT) | 1995-10-18 | — | — | EP | disclosed |
| US-5332835-A | Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process | ZAMBON S.P.A. (IT) | 1994-07-26 | — | — | US | disclosed |
| US-5243056-A | Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives | ZAMBON S.P.A. (IT) | 1993-09-07 | — | — | US | disclosed |
| US-5153328-A | 2 Hydrocarbyl-4 substituted methyl 5 (4 substituted phenyl)-oxazolines | ZAMBON S.P.A. (IT) | 1992-10-06 | — | — | US | disclosed |
| US-5105009-A | Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoropropane derivatives | ZAMBON S.P.A. (IT) | 1992-04-14 | — | — | US | disclosed |
| US-4743700-A | Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds | ZAMBON S.P.A. (IT) | 1988-05-10 | — | — | US | disclosed |
| EP-0130633-A2 | Process for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives | ZAMBON GROUP S.p.A. (IT) | 1985-01-09 | — | — | EP | disclosed |