Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.66 |
| ▸ | TTR | P02766 | 4/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | P4HB | P07237 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15036 | 0.98 | UNG (0.68) | UNGTTRFBP1P4HBCA12 | |
| SCHEMBL21777904 | 0.98 | UNG (0.68) | UNGTTRFBP1P4HBCA12 | |
| SCHEMBL29373775 | 0.98 | UNG (0.68) | UNGTTRFBP1P4HBCA12 | |
| Benzene SCHEMBL16487418 | 0.98 | UNG (0.68) | UNGTTRFBP1P4HBCA12 | |
| Bromide SCHEMBL3626512 | 0.96 | UNG (0.66) | UNGTTRFBP1P4HBCA12 | |
| Hydrochloric Acid SCHEMBL2907557 | 0.96 | UNG (0.66) | UNGTTRFBP1P4HBCA12 | |
| Isophthalic Acid SCHEMBL28305860 | 0.88 | UNG (0.60) | UNGTTRFBP1CA12CA1 | |
| Terephthalic Acid SCHEMBL6270577 | 0.85 | UNG (0.56) | UNGTTRFBP1CA12CA1 | |
| SCHEMBL28242748 | 0.83 | TDP1 (0.52) | UNGTTRFBP1PTGS2TDP1 | |
| SCHEMBL1941954 | 0.82 | ATM (0.63) | UNGPTGS2HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795347-B2 | Multi-branched polymer, process for producing the same, and applications thereof | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| EP-1396504-B1 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | MITSUI CHEMICALS INC (JP) | 2009-01-14 | — | — | EP | disclosed |
| EP-1457512-B1 | Multi-branched polymer, process for producing the same, and applications thereof | MITSUI CHEMICALS INC (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-7067587-B2 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | MITSUI CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20040242791-A1 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | MITSUI CHEMICALS, INC. (JP) | 2004-12-02 | — | — | US | disclosed |
| US-20040220346-A1 | Multi-branched polymer, process for producing the same, and applications thereof | MITSUI CHEMICALS, INC. (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1457512-A1 | Multi-branched polymer, process for producing the same, and applications thereof | Mitsui Chemicals, Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1396504-A2 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | Mitsui Chemicals, Inc. (JP) | 2004-03-10 | — | — | EP | disclosed |