Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923701 | 0.92 | SMO (0.41) | SMOSCN9ACARM1LMNASMN1; SMN2 | |
| SCHEMBL30090676 | 0.91 | SMO (0.41) | SMOSCN9ACARM1LMNASMN1; SMN2 | |
| SCHEMBL302188 | 0.91 | SMO (0.41) | SMOSCN9ACARM1LMNASMN1; SMN2 | |
| SCHEMBL1922092 | 0.90 | SMO (0.42) | SMOLMNASMN1; SMN2 | |
| SCHEMBL301924 | 0.89 | SMO (0.41) | SMOSCN9ALMNASMN1; SMN2 | |
| SCHEMBL30090694 | 0.89 | SMO (0.41) | SMOSCN9ALMNASMN1; SMN2 | |
| SCHEMBL303876 | 0.83 | SMO (0.43) | SMOCARM1 | |
| SCHEMBL1922033 | 0.82 | SMO (0.39) | SMOCARM1 | |
| SCHEMBL21819920 | 0.82 | SMO (0.39) | SMOCARM1 | |
| SCHEMBL30090530 | 0.82 | SMO (0.39) | SMOCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027746-A2 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2010-03-11 | — | — | WO | disclosed |