Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766429 | 0.84 | APP (0.62) | ESR1ESR2IKBKBSMN1; SMN2APP | |
| SCHEMBL3144306 | 0.83 | ESR1 (0.73) | ESR1ESR2IKBKBAPPHDAC6 | |
| SCHEMBL20473171 | 0.81 | MAPT (0.46) | ESR1ESR2SMN1; SMN2APPNPC1 | |
| SCHEMBL3627359 | 0.80 | KDM4E (0.47) | ESR1SMN1; SMN2RAB9AGAATP53 | |
| SCHEMBL2756691 | 0.78 | IKBKB (0.41) | ESR1ESR2IKBKBSMN1; SMN2APP | |
| SCHEMBL14985732 | 0.78 | IKBKB (0.44) | ESR1ESR2IKBKBSMN1; SMN2NPC1 | |
| SCHEMBL3621380 | 0.78 | ESR1 (0.68) | ESR1ESR2APPHDAC6 | |
| SCHEMBL26292185 | 0.77 | ESR1 (0.44) | ESR1ESR2IKBKBAPPSTK17B | |
| SCHEMBL31357470 | 0.77 | STK17B (0.44) | IKBKBSMN1; SMN2NPC1RAB9ASTK17B | |
| SCHEMBL26040038 | 0.76 | ESR1 (0.66) | ESR1ESR2APPHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207218-B1 | FIELD EFFECT TRANSISTOR | NIPPON KAYAKU KK (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-2207218-A1 | FIELD EFFECT TRANSISTOR | Nippon Kayaku Kabushiki Kaisha (JP) | 2010-07-14 | — | — | EP | disclosed |