Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 16/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966885 | 0.93 | S1PR1 (0.69) | S1PR1HSD17B10MAPTKDM4EALDH1A1 | |
| SCHEMBL1969999 | 0.92 | HSD17B10 (0.56) | S1PR1HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1965848 | 0.85 | S1PR1 (0.52) | S1PR1HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1964962 | 0.85 | S1PR1 (0.64) | S1PR1HSD17B10MAPTKDM4EALDH1A1 | |
| SCHEMBL1970592 | 0.82 | S1PR1 (0.44) | S1PR1HSD17B10MAPTKDM4EALDH1A1 | |
| SCHEMBL1967851 | 0.80 | S1PR1 (0.77) | S1PR1HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1966747 | 0.79 | S1PR1 (0.69) | S1PR1HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1970812 | 0.79 | S1PR1 (0.60) | S1PR1HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1966161 | 0.79 | S1PR1 (0.68) | S1PR1HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1966359 | 0.79 | KDM4E (0.55) | S1PR1HSD17B10KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043377-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |