SCHEMBL3628030

SCHEMBL3628030

N#Cc1ccc(Br)c(Br)n1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SOS2 Q07890 1/20 0.38
NQO1 P15559 1/20 0.36
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CTSB P07858 2/20 0.31
SRC P12931 1/20 0.31
CTSK P43235 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29560656 0.82 NQO1 (0.38) SOS2NQO1MAPK1CTSK
SCHEMBL2981097 0.82 NQO1 (0.38) SOS2NQO1MAPK1CTSK
SCHEMBL1848158 0.77 SOS2 (0.36) SOS2NQO1MAPK1L3MBTL1
SCHEMBL23795443 0.77 SOS2 (0.36) SOS2NQO1L3MBTL1
SCHEMBL10268214 0.77 SOS2 (0.48) SOS2NQO1MAPK1L3MBTL1CTSB
SCHEMBL11916709 0.77 SOS2 (0.36) SOS2NQO1L3MBTL1
SCHEMBL149575 0.77 EGLN2 (0.39) SOS2NQO1MAPK1CTSK
SCHEMBL16914426 0.77 HTT (0.42) SOS2NQO1
SCHEMBL29882642 0.77 HTT (0.42) SOS2NQO1
SCHEMBL930182 0.73 NQO1 (0.46) NQO1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed