Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555273 | 0.90 | HDAC1 (0.62) | HDAC1HDAC2 | |
| SCHEMBL3554438 | 0.87 | HDAC1 (0.60) | HDAC1HDAC2 | |
| SCHEMBL3546721 | 0.81 | NPC1 (0.53) | HDAC1HDAC2 | |
| SCHEMBL3549025 | 0.78 | HDAC1 (0.66) | HDAC1HDAC2 | |
| SCHEMBL3554880 | 0.75 | HDAC1 (0.56) | HDAC1HDAC2 | |
| SCHEMBL3550002 | 0.74 | HDAC1 (0.56) | HDAC1HDAC2 | |
| SCHEMBL3546467 | 0.74 | HDAC1 (0.58) | HDAC1HDAC2 | |
| SCHEMBL3557664 | 0.74 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL3560199 | 0.74 | HDAC1 (0.71) | HDAC1HDAC2 | |
| SCHEMBL3551388 | 0.74 | HDAC1 (0.60) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732475-B2 | Histone deacetylase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-20070015809-A1 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015809-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC3, HDAC5 | HDAC1 1/4885HDAC2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.