⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346194 | 0.74 | — | — | |
| Iodide SCHEMBL8539252 | 0.71 | — | — | |
| SCHEMBL5728366 | 0.67 | — | — | |
| SCHEMBL1937504 | 0.67 | — | — | |
| SCHEMBL11156577 | 0.67 | — | — | |
| SCHEMBL10979378 | 0.65 | — | — | |
| SCHEMBL2379315 | 0.63 | — | — | |
| SCHEMBL24348579 | 0.63 | — | — | |
| SCHEMBL23213395 | 0.59 | — | — | |
| SCHEMBL23213535 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108892637-A | SHIP1 regulator and relative method | 阿奎诺克斯药物（加拿大）公司 | 2018-11-27 | — | — | CN | disclosed |
| CN-105164108-B | SHIP1 modulators and methods related thereto | 阿奎诺克斯药物（加拿大）公司 | 2018-07-17 | — | — | CN | disclosed |
| US-9777020-B2 | Furo-3-carboxamide derivatives and methods of use | ABBVIE INC. (US) | 2017-10-03 | — | — | US | disclosed |
| EP-3097095-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | AbbVie Inc. (US) | 2016-11-30 | — | — | EP | disclosed |
| EP-2396330-B1 | FUSED PYRIMIDINES | BAYER IP GMBH (DE) | 2016-04-06 | — | — | EP | disclosed |
| CN-105164108-A | SHIP1 modulators and methods related thereto | AQUINOX PHARMACEUTICALS INC | 2015-12-16 | — | — | CN | disclosed |
| US-20150210720-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | ABBVIE INC. | 2015-07-30 | — | — | US | disclosed |
| WO-2015112754-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | ABBVIE INC. (US) | 2015-07-30 | — | — | WO | disclosed |
| US-8957064-B2 | Fused pyrimidines | BAYER INTELLECTUAL PROPERTY GMBH (US) | 2015-02-17 | — | — | US | disclosed |
| WO-2015009882-A2 | CYANO DERIVATIVES AND THEIR USES | THE HAMNER INSTITUTES (US) | 2015-01-22 | — | — | WO | disclosed |
| US-4287198-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-09-01 | — | — | US | disclosed |
| US-4228291-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-14 | — | — | US | disclosed |
| US-4221802-A | Pharmacologically active guanidine compounds for inhibiting H-2 histamine receptors | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-09-09 | — | — | US | disclosed |
| US-4171325-A | Chemical process | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-16 | — | — | US | disclosed |
| US-4154844-A | ANTIHISTAMINE, GASTRIC JUICE ANTISECRETORY AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4137237-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |
| US-4024271-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4022797-A | PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-10 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |