Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.76 |
| ▸ | ACHE | P22303 | 14/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625938 | 1.00 | EPHX2 (0.76) | EPHX2ACHEPLA2G2AADRA1AEPHX1 | |
| SCHEMBL1077924 | 1.00 | EPHX2 (0.76) | EPHX2ACHEPLA2G2AADRA1AEPHX1 | |
| SCHEMBL19400416 | 1.00 | EPHX2 (0.76) | EPHX2ACHEPLA2G2AADRA1AEPHX1 | |
| SCHEMBL19400387 | 1.00 | EPHX2 (0.76) | EPHX2ACHEPLA2G2AADRA1AEPHX1 | |
| SCHEMBL19400357 | 1.00 | EPHX2 (0.76) | EPHX2ACHEPLA2G2AADRA1AEPHX1 | |
| SCHEMBL19400363 | 1.00 | EPHX2 (0.76) | EPHX2ACHEPLA2G2AADRA1AEPHX1 | |
| SCHEMBL3655324 | 0.98 | EPHX2 (0.74) | EPHX2ACHEPLA2G2A | |
| SCHEMBL8920145 | 0.95 | EPHX2 (0.84) | EPHX2ACHEPLA2G2AEPHX1 | |
| SCHEMBL9190902 | 0.95 | EPHX2 (0.84) | EPHX2ACHEPLA2G2AEPHX1 | |
| SCHEMBL9830221 | 0.95 | EPHX2 (0.84) | EPHX2ACHEPLA2G2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163808-A1 | COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION | 学校法人慶應義塾 | 2017-09-28 | — | — | WO | disclosed |
| EP-2200439-A1 | HDAC INHIBITORS | Lixte Biotechnology, Inc. (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009045440-A1 | HDAC INHIBITORS | LIXTE BIOTECHNOLOGY HOLDINGS, INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| EP-1745044-A2 | BENZOTHIAZOLE DERIVATIVES HAVING CDK MODULATING ACTIVITY AND USE THEREOF AS ANTICANCER AGENTS | Aventis Pharma S.A. (FR) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005097787-A2 | NOVEL BENZOTHIAZOLES AND THE USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA S.A. (FR) | 2005-10-20 | — | — | WO | disclosed |