SCHEMBL3629670

SCHEMBL3629670

O=C(O)c1ccc(Br)c(Br)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.50
ALOX15 P16050 3/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ACMSD Q8TDX5 1/20 0.50
ALDH1A1 P00352 3/20 0.47
MGAM O43451 1/20 0.45
LMNA P02545 3/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
P4HTM Q9NXG6 2/20 0.39
P4HA1 P13674 1/20 0.39
MIF P14174 1/20 0.39
HIF1A Q16665 1/20 0.38
MCL1 Q07820 1/20 0.38
KDM5A P29375 1/20 0.37
JMJD1C Q15652 1/20 0.37
KDM3A Q9Y4C1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14152594 0.83 KDM4E (0.48) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL3648082 0.80 KDM4E (0.48) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL15898801 0.80 KDM4E (0.48) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL934791 0.80 KDM4E (0.48) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL11990346 0.80 KDM4E (0.48) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL30194732 0.78 KDM4E (0.48) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL4019382 0.78 KDM4E (0.46) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL1425108 0.78 KDM4E (0.56) KDM4EALOX15TSHRTDP1ACMSD
Hydrochloric Acid SCHEMBL28367308 0.78 KDM4E (0.46) KDM4EALOX15TSHRTDP1ACMSD
SCHEMBL30012630 0.78 KDM4E (0.46) KDM4EALOX15TSHRTDP1ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024009283-A1 AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-01-11 WO disclosed
WO-2024009283-A1 AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-01-11 WO disclosed
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
EP-1248867-A1 SELECTIVE ELECTROCHEMICAL REDUCTION OF HALOGENATED 4-AMINOPICOLINIC ACIDS Dow AgroSciences LLC (US) 2002-10-16 EP disclosed
EP-1246802-A1 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 2002-10-09 EP disclosed
WO-2001051684-A1 SELECTIVE ELECTROCHEMICAL REDUCTION OF HALOGENATED 4-AMINOPICOLINIC ACIDS DOW AGROSCIENCES, LLC (US) 2001-07-19 WO disclosed
WO-2001051468-A1 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2001-07-19 WO disclosed