Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.66 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | PTGIR | P43119 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055326 | 0.90 | PTGDR2 (0.75) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2501697 | 0.84 | PTGDR2 (0.71) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1057389 | 0.84 | PTGDR2 (0.81) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL153039 | 0.83 | PTGDR2 (0.70) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1055322 | 0.83 | PTGDR2 (0.73) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3627264 | 0.83 | PTGDR2 (0.73) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL153095 | 0.82 | PTGDR2 (0.77) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL138678 | 0.82 | PTGDR2 (0.75) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL153719 | 0.82 | PTGDR2 (0.69) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL153213 | 0.82 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245022-A2 | ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-11-03 | — | — | EP | claimed |
| WO-2009108720-A2 | ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-09-03 | — | — | WO | claimed |