SCHEMBL3631347

SCHEMBL3631347

COC1(Br)C=CC=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21597036 0.76
SCHEMBL28166441 0.68
SCHEMBL3442717 0.67
SCHEMBL4300067 0.67
SCHEMBL18585114 0.67
SCHEMBL10512160 0.67
SCHEMBL6510676 0.67
SCHEMBL28787552 0.67
Hydrochloric Acid SCHEMBL22031511 0.66
SCHEMBL27940574 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725301-A Preparation method of 1,2-dihydropyridin-2-one derivative BEIJING LABWORLD BIO MEDICINE TECHNOLOGY CO LTD 2015-06-24 CN claimed
CN-104649963-A Preparation technology of perampanel intermediate SUZHOU LAKESTAR PHARMATECH CO LTD 2015-05-27 CN claimed
CN-102491862-B Method for preparing biaryl compound in pure water UNIV DALIAN TECH 2014-06-25 CN claimed
CN-103588597-A Method for preparing biaryl compound in pure water UNIV DALIAN TECH 2014-02-19 CN claimed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
WO-2023191469-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING PHENYL GROUP AND USES THEREOF 주식회사 비엔에이치리서치 2023-10-05 WO disclosed
CN-110452216-A Anti-fibrosis pyridinone INTERMUNE INC 2019-11-15 CN disclosed
CN-106928194-B Compounds for the treatment of premature aging and especially premature aging ABIVAX公司 2019-11-12 CN disclosed
CN-106715413-B piperazine derivatives as liver X receptor modulators VITAE PHARMACEUTICALS, INC. (US) 2019-11-01 CN disclosed
CN-110382494-A Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors 阿雷生物药品公司 2019-10-25 CN disclosed
CN-105085382-B Pyrrole Lun Panai isomers crystal form and its preparation method and application 江苏豪森药业集团有限公司 2019-10-18 CN disclosed
CN-101687842-B Modulators of CFTR VERTEX PHARMA 2013-03-06 CN disclosed
CN-102753526-A Pyridinone hydroxycyclopentyl carboxamides: HIV integrase inhibitors with therapeutic applications UNIV GEORGIA 2012-10-24 CN disclosed
CN-1585640-B N-adamantylmethyl derivates and intermediates as pharmaceutical compositions and processes for their preparation ASTRAZENECA AB 2010-10-27 CN disclosed
EP-2142512-A2 IMIDAZOLIDINE CARBOXAMIDE DERIVATIVES AS P2X7 MODULATORS Glaxo Group Limited (GB) 2010-01-13 EP disclosed
WO-2008119825-A2 IMIDAZOLIDINE CARBOXAMIDE DERIVATIVES AS P2X7 MODULATORS GLAXO GROUP LIMITED (GB) 2008-10-09 WO disclosed
EP-1858876-A2 PYRIDINONE DERIVATIVES AGAINST MALARIA GLAXO GROUP LIMITED (GB) 2007-11-28 EP disclosed
WO-2006094799-A2 PYRIDINONE DERIVATIVES AGAINST MALARIA GLAXO GROUP LIMITED (GB) 2006-09-14 WO disclosed
CN-1585640-A N-adamantylmethyl derivates and intermediates as pharmaceutical compositions and processes for their preparation ASTRAZENECA AB (SE) 2005-02-23 CN disclosed