⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484865 | 0.74 | — | — | |
| SCHEMBL5772044 | 0.74 | — | — | |
| SCHEMBL8860252 | 0.69 | — | — | |
| SCHEMBL18721816 | 0.53 | — | — | |
| SCHEMBL2365826 | 0.53 | — | — | |
| SCHEMBL3463247 | 0.51 | — | — | |
| SCHEMBL7514573 | 0.51 | — | — | |
| SCHEMBL3826416 | 0.51 | — | — | |
| SCHEMBL1315681 | 0.49 | — | — | |
| SCHEMBL13782516 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155203-A1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | ChemoCentryx Inc (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008147822-A1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2008-12-04 | — | — | WO | disclosed |