Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865370 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL679960 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL866919 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL866380 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL865371 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL866918 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL866210 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL866211 | 1.00 | APP (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL864690 | 0.99 | MAPT (0.40) | APPMAPTKDM4EABCB1ABCC1 | |
| SCHEMBL864691 | 0.99 | MAPT (0.40) | APPMAPTKDM4EABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142957-A1 | METHOD OF UNIFORM AND DEFECT FREE LIQUID CRYSTAL ALIGNING LAYERS | Rolic AG (CH) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008119449-A1 | METHOD OF UNIFORM AND DEFECT FREE LIQUID CRYSTAL ALIGNING LAYERS | ROLIC AG (CH) | 2008-10-09 | — | — | WO | disclosed |