⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873091 | 0.80 | — | — | |
| SCHEMBL1803267 | 0.77 | — | — | |
| SCHEMBL27871893 | 0.77 | CA1 (0.39) | — | |
| SCHEMBL6717661 | 0.75 | — | — | |
| SCHEMBL28784786 | 0.73 | ZDHHC7 (0.43) | — | |
| SCHEMBL5274646 | 0.73 | GAA (0.48) | — | |
| SCHEMBL10931936 | 0.73 | — | — | |
| SCHEMBL1025291 | 0.73 | HDAC6 (0.38) | — | |
| SCHEMBL514695 | 0.72 | — | — | |
| SCHEMBL16215738 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-B | CK2 inhibitors, compositions and methods thereof | 北极星药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109265400-B | Arginine methyltransferase inhibitors and uses thereof | EPIZYME股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-109415357-B | Condensed heterocyclic compound having hydrazone group or salt thereof, agricultural and horticultural insecticide containing the compound, and method for using the same | 日本农药株式会社 | 2021-10-29 | — | — | CN | disclosed |
| EP-3508485-B1 | HYDRAZONYL GROUP CONTAINING-CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO LTD (JP) | 2021-02-24 | — | — | EP | disclosed |
| US-10377754-B2 | Hydrazonyl group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
| US-10377754-B2 | Hydrazonyl group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
| EP-3508485-A1 | FUSED HETEROCYCLIC COMPOUND HAVING HYDRAZONYL GROUP OR SALTS THEREOF, PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | Nihon Nohyaku Co., Ltd. (JP) | 2019-07-10 | — | — | EP | disclosed |
| US-20190177319-A1 | HYDRAZONYL GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2019-06-13 | — | — | US | disclosed |
| US-20190177319-A1 | HYDRAZONYL GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2019-06-13 | — | — | US | disclosed |
| CN-109415357-A | Condensed heterocyclic compounds or its esters with hydrazone group and salt, garderning pesticide and its application method containing the compound | 日本农药株式会社 | 2019-03-01 | — | — | CN | disclosed |
| US-20170291905-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-12 | — | — | US | disclosed |
| CN-102917590-B | Tricyclic compound and the PBK inhibitor containing described compound | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | disclosed |
| EP-2144898-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-2004595-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | Schering-Plough Ltd. (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008130021-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-30 | — | — | WO | disclosed |
| WO-2007116314-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (US) | 2007-10-18 | — | — | WO | disclosed |
| US-20070238700-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (CH) | 2007-10-11 | — | — | US | disclosed |
| EP-0396769-A1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1990-11-14 | — | — | EP | disclosed |