Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868166 | 0.83 | AKT1 (0.59) | AKT1AKT2 | |
| SCHEMBL538387 | 0.81 | AKT1 (0.58) | AKT1AKT2 | |
| SCHEMBL363324 | 0.81 | AKT1 (0.61) | AKT1AKT2 | |
| SCHEMBL538715 | 0.81 | AKT1 (0.59) | AKT1AKT2 | |
| SCHEMBL868013 | 0.81 | AKT1 (0.56) | AKT1AKT2 | |
| SCHEMBL361966 | 0.80 | AKT1 (0.56) | AKT1AKT2 | |
| SCHEMBL867156 | 0.80 | AKT1 (0.60) | AKT1AKT2 | |
| SCHEMBL538499 | 0.80 | AKT1 (0.56) | AKT1AKT2 | |
| SCHEMBL866992 | 0.79 | AKT1 (0.57) | AKT1AKT2 | |
| SCHEMBL538686 | 0.79 | AKT1 (0.64) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593458-A1 | BICYCLIC PYRIMIDINES | Bayer Intellectual Property GmbH (DE) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007416-A1 | BICYCLIC PYRIMIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |