SCHEMBL3633804

SCHEMBL3633804

CCCCCNCCC(=O)OC

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.61
CA14 Q9ULX7 3/20 0.61
CA2 P00918 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
TSHR P16473 4/20 0.54
ALDH1A1 P00352 1/20 0.54
EPHX1 P07099 3/20 0.48
EPHX2 P34913 1/20 0.46
POLB P06746 1/20 0.46
POLA1 P09884 1/20 0.46
S1PR2 O95136 5/20 0.46
S1PR4 O95977 5/20 0.46
S1PR1 P21453 5/20 0.46
S1PR3 Q99500 5/20 0.46
S1PR5 Q9H228 1/20 0.46
PAOX Q6QHF9 1/20 0.44
CASP2 P42575 1/20 0.44
KDM5A P29375 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19032581 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
SCHEMBL25242593 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
Hydrochloric Acid SCHEMBL5176696 0.98 CA12 (0.59) CA12CA14CA2CA7CA9
SCHEMBL25211563 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
SCHEMBL25215770 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
SCHEMBL25246754 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
SCHEMBL25259864 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
SCHEMBL25214012 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
SCHEMBL2748412 0.98 CA12 (0.64) CA12CA14CA2CA7CA9
SCHEMBL25257740 0.98 CA12 (0.64) CA12CA14CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1807090-A2 PROCESS FOR THE PREPARATION OF IBANDRONATE F. Hoffmann-La Roche AG (CH) 2007-07-18 EP claimed
WO-2006045578-A2 PROCESS FOR THE PREPARATION OF IBANDRONATE F. HOFFMANN-LA ROCHE AG (CH) 2006-05-04 WO claimed
EP-2144919-A2 MULTI STEP SYNTHESIS OF IBANDRONATE F. Hoffmann-Roche AG (CH) 2010-01-20 EP disclosed
WO-2009093258-A2 A NEW AND IMPROVED PROCESS FOR THE PREPARATION OF IBANDRONATE SODIUM MONOHYDRATE FLEMING LABORATORIES LIMITED (IN) 2009-07-30 WO disclosed
WO-2008125483-A2 MULTI STEP SYNTHESIS OF IBANDRONATE F. HOFFMANN-LA ROCHE AG (CH) 2008-10-23 WO disclosed
EP-1807090-A2 PROCESS FOR THE PREPARATION OF IBANDRONATE F. Hoffmann-La Roche AG (CH) 2007-07-18 EP disclosed
WO-2006045578-A2 PROCESS FOR THE PREPARATION OF IBANDRONATE F. HOFFMANN-LA ROCHE AG (CH) 2006-05-04 WO disclosed