Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633856 | 0.89 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL27965204 | 0.89 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL2162235 | 0.87 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL14659707 | 0.87 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL14659581 | 0.86 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL14659969 | 0.86 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL2163302 | 0.85 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL2162212 | 0.85 | TRPV1 (0.88) | TRPV1 | |
| SCHEMBL2164008 | 0.85 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL2162068 | 0.84 | TRPV1 (1.00) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150531-A2 | NOVEL VANILLOID RECEPTOR LIGANDS, AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008125295-A2 | NOVEL VANILLOID RECEPTOR LIGANDS, AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | disclosed |