SCHEMBL3634048

SCHEMBL3634048

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nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
CYP3A4 P08684 1/20 0.37
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
GRIK1 P39086 2/20 0.33
GRIK2 Q13002 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3637092 1.00 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL3634453 0.93 GRIK1 (0.41) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL15760500 0.88 SMN1; SMN2 (0.34) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL2286672 0.85 MAPT (0.40) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL2516533 0.85 MAPT (0.40) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL557341 0.85 MAPT (0.35) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL8628768 0.83 TDP1 (0.35) MAPTCACNA1BAPBA1CYP3A4TSHR
Hydrochloric Acid SCHEMBL6573325 0.83 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
Hydrochloric Acid SCHEMBL2302935 0.83 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
Hydrochloric Acid SCHEMBL2302945 0.83 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020017390-A1 LACTIC ACID BACTERIUM, NATURAL IMMUNE ACTIVATING AGENT DERIVED FROM LACTIC ACID BACTERIUM, AND PREVENTIVE/THERAPEUTIC DRUG FOR INFECTION AND FOOD OR BEVERAGE 株式会社ゲノム創薬研究所 2020-01-23 WO disclosed
US-8343212-B2 Polymer coatings on medical devices Biotectix, LLC (US) 2013-01-01 US disclosed
EP-2155275-B1 POLYMER COATINGS ON MEDICAL DEVICES BIOTECTIX LLC (US) 2012-09-05 EP disclosed
US-20100312331-A1 POLYMER COATINGS ON MEDICAL DEVICES CHAMELEON BIOSURFACES LIMITED (GB) 2010-12-09 US disclosed
EP-2155275-A2 POLYMER COATINGS ON MEDICAL DEVICES Chameleon Biosurfaces Limited (GB) 2010-02-24 EP disclosed
WO-2008139200-A2 POLYMER COATINGS ON MEDICAL DEVICES CHAMELEON BIOSURFACES LIMITED (GB) 2008-11-20 WO disclosed