SCHEMBL363499

SCHEMBL363499

CC(C)(C)[CH]CC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7375676 0.69 TSHR (0.41) TSHRTDP1
SCHEMBL10897274 0.67
SCHEMBL15302566 0.67
SCHEMBL4294983 0.67 TSHR (0.36) TSHRTDP1
SCHEMBL17721454 0.65 TSHR (0.30) TSHRTDP1
SCHEMBL4653084 0.65
SCHEMBL93549 0.64
Fluoride SCHEMBL11521122 0.64 TSHR (0.33) TSHRTDP1
SCHEMBL13805617 0.62
SCHEMBL21884 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016124694-A1 LIGHT ABSORBER Technische Universität Dresden (DE) 2016-08-11 WO claimed
EP-1165569-B1 BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES AGILENT TECHNOLOGIES INC (US) 2005-08-10 EP claimed
EP-1165569-A1 BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES Agilent Technologies, Inc. (US) 2002-01-02 EP claimed
WO-2000056740-A1 BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES PROLINX, INC. (US) 2000-09-28 WO claimed
US-6031117-A Boronic acid containing phosphoramidite reagents PROLINX INCORPORATED (US) 2000-02-29 US claimed
US-6013783-A Boronic acid containing oligonucleotides and polynucleotides PROLINX INCORPORATED (US) 2000-01-11 US claimed
EP-0261755-B1 FIVE-MEMBERED HETEROCYCLIC DERIVATIVES OF N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1992-12-16 EP claimed
EP-0245950-B1 INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1992-06-17 EP claimed
EP-0236618-B1 INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP claimed
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-21 US disclosed
EP-4144747-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-08 EP disclosed
US-20230069218-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-02 US disclosed
EP-3395796-B1 A CRYSTALLINE TRIHYDRATE FORM OF (3S,3S') 4,4'-DISULFANEDIYLBIS (3-AMINOBUTANE 1-SULFONIC ACID) QUANTUM GENOMICS (FR) 2021-11-24 EP disclosed
EP-3455889-A1 PHOSPHORESCENT LIGHT-EMITTING COMPLEX AND USE IN LIGHT-EMITTING DEVICE Cambridge Display Technology Limited (GB) 2019-03-20 EP disclosed
WO-1995001351-A1 SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1995-01-12 WO disclosed
WO-1994019346-A1 SUBSTITUTED HETEROARYLALKYLTHIOPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1994-09-01 WO disclosed
WO-1994013290-A1 USE OF ALKYLTHIOPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1994-06-23 WO disclosed
EP-0086826-A4 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES. FMC CORP (US) 1983-12-23 EP disclosed
EP-0086826-A1 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES. FMC CORP (US) 1983-08-31 EP disclosed
WO-1983000870-A1 ALPHA-BRANCHED ALKYLTHIOPHOSPHATE PESTICIDES FMC CORP (US) 1983-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230069218-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID MRPL21, RPL41, RPL21 TSHR 3420/4885TDP1 2693/4885
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES NGLY1, VIP, DNPEP TSHR 3595/4885TDP1 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.