Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11303263 | 0.81 | KMT2A (0.58) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL568903 | 0.81 | KMT2A (0.58) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL2799510 | 0.81 | KMT2A (0.63) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL10887061 | 0.79 | KMT2A (0.50) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL10816148 | 0.78 | TSHR (0.48) | KMT2AMEN1POLBTSHRMAPK1 | |
| Atrolactamide SCHEMBL78236 | 0.78 | MAPT (0.65) | KMT2APOLBTSHRHIF1AMAPT | |
| SCHEMBL11699545 | 0.78 | SRD5A2 (0.55) | KMT2AMEN1TSHRSMN1; SMN2MAPT | |
| SCHEMBL6203218 | 0.78 | POLB (0.55) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL29570723 | 0.77 | MEN1 (0.48) | KMT2AMEN1POLBTSHRMAPK1 | |
| SCHEMBL11836094 | 0.76 | KMT2A (0.52) | KMT2AMEN1POLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593424-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | Medeia Therapeutics Ltd (FI) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007644-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | MEDEIA THERAPEUTICS LTD (FI) | 2012-01-19 | — | — | WO | claimed |