Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223202 | 1.00 | KCNH2 (0.40) | KCNH2MAOAMAOBGRM2CCR8 | |
| SCHEMBL1223168 | 0.95 | KCNH2 (0.39) | KCNH2MAOAMAOBCCR8 | |
| SCHEMBL3633994 | 0.95 | KCNH2 (0.39) | KCNH2MAOAMAOBCCR8 | |
| SCHEMBL1223668 | 0.90 | GRM2 (0.34) | KCNH2GRM2 | |
| SCHEMBL3630803 | 0.90 | GRM2 (0.34) | KCNH2GRM2 | |
| SCHEMBL1223921 | 0.87 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL3634537 | 0.87 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL1224482 | 0.83 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL1222598 | 0.83 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL1224485 | 0.83 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | claimed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | claimed |
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |