⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18371681 | 0.79 | — | — | |
| SCHEMBL290724 | 0.78 | — | — | |
| SCHEMBL347422 | 0.76 | — | — | |
| SCHEMBL6051551 | 0.76 | — | — | |
| SCHEMBL12257056 | 0.75 | — | — | |
| SCHEMBL13297826 | 0.74 | — | — | |
| SCHEMBL20604223 | 0.74 | — | — | |
| SCHEMBL9994026 | 0.74 | — | — | |
| Hydrogen Sulfide SCHEMBL28240009 | 0.74 | — | — | |
| SCHEMBL1702961 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 563 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332955-B | Cefditoren pivoxil Process for the preparation of intermediates | 深圳六合六医疗器械有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-115289272-B | 4-Methylthiazole-5-formaldehyde production is with split phase solution discharge valve | 东营曜康医药科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-115430192-B | Filter pressing equipment is used in production of 4-methylthiazole-5-formaldehyde | 东营曜康医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117007730-A | Method for detecting 4-methylthiazole-5-formaldehyde residues in cefditoren pivoxil bulk drug | 湖北凌晟药业股份有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116867782-A | Pyrazole amide derivative | 豪夫迈·罗氏有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-116332955-A | Preparation method of cefditoren pivoxil intermediate | 深圳六合六医疗器械有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115925649-A | Method for preparing 4-methylthiazole-5-formaldehyde by continuous flow | 深圳市茵诺圣生物科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-112724101-B | Synthetic method of 4-methylthiazole-5-formaldehyde | 杭州凯方科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-115430192-A | Filter pressing equipment for producing 4-methylthiazole-5-formaldehyde | 东营曜康医药科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115289272-A | Split-phase solution discharge valve for production of 4-methylthiazole-5-formaldehyde | 东营曜康医药科技有限公司 | 2022-11-04 | — | — | CN | claimed |
| WO-2005003141-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFDITOREN | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2005-01-13 | — | — | WO | claimed |
| US-6833459-B2 | Reducing thiazole ester to thiazole alcohol using sodium borohydride in the presence of aluminum chloride in a solvent and oxidising the thiazole alcohol to obtain 4-methyl-5-formyl-thiazole | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-12-21 | — | — | US | claimed |
| CN-1495176-A | 4-methyl-5-formylthiazole preparation method | 日本化学工业株式会社 | 2004-05-12 | — | — | CN | claimed |
| WO-2003091230-A1 | PROCESS FOR THE PREPARATION OF 4-METHYL-THIAZOLE-5-CARBALDEHYDE INTERMEDIATE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-11-06 | — | — | WO | claimed |
| US-20030204095-A1 | Process for the preparation of thiazole intermediate | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-10-30 | — | — | US | claimed |
| US-20020107290-A1 | Benzamidine derivative | AJINOMOTO CO., INC. (JP) | 2002-08-08 | — | — | US | claimed |
| US-6410538-B2 | ANTICOAGULANT OR AN AGENT FOR TREATING OR PREVENTING THROMBI OR EMBOLI | AJINOMOTO CO., INC. (JP) | 2002-06-25 | — | — | US | claimed |
| US-20010056123-A1 | Anticoagulant or an agent for treating or preventing thrombi or emboli | AJINOMOTO CO., INC (JP) | 2001-12-27 | — | — | US | claimed |
| CN-1311771-A | Benzamidine derivative | AJINOMOTO KK (JP) | 2001-09-05 | — | — | CN | claimed |
| EP-1086946-A1 | BENZAMIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2001-03-28 | — | — | EP | claimed |