⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3631298 | 0.97 | CYP1A2 (0.39) | — | |
| Bromide SCHEMBL23929285 | 0.97 | CYP1A2 (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL28544624 | 0.97 | CYP1A2 (0.43) | — | |
| Hydrochloric Acid SCHEMBL4706089 | 0.97 | CYP1A2 (0.39) | — | |
| SCHEMBL223265 | 0.97 | — | — | |
| SCHEMBL5242776 | 0.97 | — | — | |
| SCHEMBL2442076 | 0.97 | — | — | |
| SCHEMBL29028773 | 0.97 | CYP1A2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL28544756 | 0.95 | CYP1A2 (0.42) | — | |
| SCHEMBL13078692 | 0.94 | CYP1A2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118146221-A | Pyrrolo [3,2-b ] pyridine topoisomerase inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | claimed |
| US-11939307-B2 | Phenylmethyl-piperazine derivatives and antiviral uses thereof | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2024-03-26 | — | — | US | claimed |
| CN-111491929-B | Aminoindole compounds useful as TLR inhibitors | 百时美施贵宝公司 | 2023-11-28 | — | — | CN | claimed |
| CN-111491918-B | Aryl and heteroaryl substituted indole compounds | 百时美施贵宝公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116693873-A | Hyperbranched polymer high-temperature-resistant high-salt-resistant filtrate reducer, and preparation method and application thereof | 长江大学 | 2023-09-05 | — | — | CN | claimed |
| CN-111699185-B | 6-azaindole compounds | 百时美施贵宝公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116075510-A | 1H-benzo [ d ] imidazole derivatives as TLR9 inhibitors for the treatment of fibrosis | 百时美施贵宝公司 | 2023-05-05 | — | — | CN | claimed |
| WO-2023064133-A1 | SUBSTITUTED 1H-PYRAZOLO [4,3-c] QUINOLINES, METHODS OF PREPARATION, AND USE THEREOF | LOMOND THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | claimed |
| EP-4028400-A1 | SUBSTITUTED IMIDAZOQUINOXALINE COMPOUNDS AND USES THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2022-07-20 | — | — | EP | claimed |
| CN-109593096-B | Tricyclic heterocycles as BET protein inhibitors | 因赛特公司 | 2022-01-14 | — | — | CN | claimed |
| WO-2021047646-A1 | SUBSTITUTED IMIDAZOQUINOXALINE COMPOUNDS AND USES THEREOF | IMPACT THERAPEUTICS, INC (CN) | 2021-03-18 | — | — | WO | claimed |
| CN-112480120-A | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-111918864-A | Prodrug compounds activated by AKR1C3 and their use to treat hyperproliferative disorders | 阿基利斯医疗有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111699185-A | 6-azaindole compounds | 百时美施贵宝公司 | 2020-09-22 | — | — | CN | claimed |
| CN-111491929-A | Aminoindole compounds useful as T L R inhibitors | 百时美施贵宝公司 | 2020-08-04 | — | — | CN | claimed |
| CN-111491918-A | Aryl and heteroaryl substituted indole compounds | 百时美施贵宝公司 | 2020-08-04 | — | — | CN | claimed |
| CN-111065626-A | Compounds for the treatment of huntington's chorea | PTC医疗公司 | 2020-04-24 | — | — | CN | claimed |
| CN-110698432-A | Benzyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2020-01-17 | — | — | CN | claimed |