Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640644 | 0.91 | MRGPRX1 (0.63) | MRGPRX1MAOBKDM4EMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL3645056 | 0.90 | MRGPRX1 (0.62) | MRGPRX1MAOBKDM4EMAPK1LMNA | |
| SCHEMBL3637654 | 0.87 | MRGPRX1 (0.61) | MRGPRX1MAOBAPPCTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL3638859 | 0.86 | MRGPRX1 (0.60) | MRGPRX1MAOBAPPCTNNB1TCF7L2 | |
| SCHEMBL3636984 | 0.85 | MRGPRX1 (0.79) | MRGPRX1MAOBAPPKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL3643496 | 0.84 | MRGPRX1 (0.77) | MRGPRX1MAOBAPPKDM4EMAPK1 | |
| SCHEMBL1090783 | 0.79 | MRGPRX1 (0.65) | MRGPRX1MAOBAPPKDM4EMAPK1 | |
| SCHEMBL1092285 | 0.79 | MRGPRX1 (0.65) | MRGPRX1MAOBAPPKDM4EMAPK1 | |
| SCHEMBL1090716 | 0.79 | MRGPRX1 (0.65) | MRGPRX1MAOBAPPKDM4EMAPK1 | |
| SCHEMBL1090790 | 0.78 | MRGPRX1 (0.66) | MRGPRX1APPHRH4KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173346-A2 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | Summit Corporation Plc (GB) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009001060-A2 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | SUMMIT CORPORATION PLC (GB) | 2008-12-31 | — | — | WO | disclosed |