SCHEMBL363660

SCHEMBL363660

O=C(O)c1coc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9372431 0.79
SCHEMBL3054665 0.79
SCHEMBL1476834 0.79
SCHEMBL19992920 0.73
SCHEMBL5151230 0.73
SCHEMBL26907933 0.73 NR4A2 (0.43)
SCHEMBL69933 0.73 NR4A2 (0.43)
Hydrochloric Acid SCHEMBL11689258 0.73 KDM4E (0.33)
SCHEMBL19452109 0.71
SCHEMBL4729951 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108350034-B Antimicrobial polymyxin derived compounds 莫纳什大学 2022-03-11 CN claimed
CN-119707952-B Thiadiazolidinone derivative with PTPN2/PTPN1 inhibitory activity, and preparation method and application thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN disclosed
EP-4631952-A1 GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-10-15 EP disclosed
WO-2025104701-A1 AMIDO HETEROAROMATIC COMPOUNDS ASTRAZENECA AB (SE) 2025-05-22 WO disclosed
WO-2025104699-A1 URACIL COMPOUNDS ASTRAZENECA AB (SE) 2025-05-22 WO disclosed
CN-119707952-A Thiadiazolidinone derivative with PTPN2/PTPN1 inhibitory activity, and preparation method and application thereof 中国药科大学 2025-03-28 CN disclosed
US-20250066369-A1 BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES NodThera Limited (GB) 2025-02-27 US disclosed
CN-118994142-A Furanamide compound and application thereof 浙江大学金华研究院 2024-11-22 CN disclosed
US-20240376091-A1 THIADIAZOLEAMIDE DERIVATIVES AND THEIR APPLICATIONS ZHEJIANG UNIVERSITY (CN) 2024-11-14 US disclosed
EP-4460505-A1 BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES Nodthera Limited (GB) 2024-11-13 EP disclosed
US-5300655-A 2-carboxy-thiophene derivatives PFIZER INC. (US) 1994-04-05 US disclosed
US-5290802-A 3-substituted-2-oxindole derivatives PFIZER INC. (US) 1994-03-01 US disclosed
CN-1022832-C Preparation of 3-substituted-2-oxindole derivatives PFIZER (US) 1993-11-24 CN disclosed
US-5047554-A 3-substituted-2-oxindole derivatives PFIZER INC. (US) 1991-09-10 US disclosed
EP-0399645-A2 Tetrahydropyranyl derivatives, process for their preparation and pharmaceutical or veterinary compositions containing them BEECHAM GROUP PLC (GB) 1990-11-28 EP disclosed
CN-1046525-A 3-SUBSTITUTED-2-OXINDOLE DERIVATIVES PFIZER (US) 1990-10-31 CN disclosed
EP-0393936-A1 3-substituted-2-oxindole derivatives as antiinflammatory agents PFIZER INC. (US) 1990-10-24 EP disclosed
CN-1046332-A New compound BEECHAM GROUP PLC (GB) 1990-10-24 CN disclosed
US-4282246-A Antidiabetic furancarboxylic and thiphenecarboxylic acids PFIZER INC. (US) 1981-08-04 US disclosed
US-4000164-A SUBSTITUTED FUROYLACETIC ACIDS AND ESTERS RICHARDSON-MERRELL INC. (US) 1976-12-28 US disclosed