SCHEMBL3637501

SCHEMBL3637501

CCCCCCCCC#CCC#CCCCCCCC(=O)O

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.93
RECQL P46063 2/20 0.93
PTPN7 P35236 5/20 0.89
ALDH1A1 P00352 3/20 0.89
MEN1 O00255 2/20 0.89
KMT2A Q03164 2/20 0.89
KDM4E B2RXH2 1/20 0.89
USP2 O75604 1/20 0.89
POLB P06746 1/20 0.89
MAPT P10636 1/20 0.89
HPGD P15428 1/20 0.89
ALOX12 P18054 1/20 0.89
BLM P54132 1/20 0.89
MCL1 Q07820 1/20 0.89
SMN1; SMN2 Q16637 1/20 0.89
HMGCR P04035 3/20 0.89
EPHX2 P34913 1/20 0.68
GPR84 Q9NQS5 6/20 0.65
PPARG P37231 6/20 0.65
PPARD Q03181 6/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28742735 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL28742727 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL31189074 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL31189030 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL10919700 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL4863654 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL47069 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL11525377 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL2733500 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1
SCHEMBL28742745 1.00 TDP1 (0.93) TDP1RECQLPTPN7ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023213310-A9 CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF 太阳雨林(北京)生物医药有限公司 2025-02-20 WO disclosed
WO-2023213310-A1 CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF 太阳雨林(北京)生物医药有限公司 2023-11-09 WO disclosed
US-20190054186-A1 Magnetic Nanoparticle-Polymer Complexes and uses Thereof THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2019-02-21 US disclosed
WO-2017173205-A1 MAGNETIC NANOPARTICLE-POLYMER COMPLEXES AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2017-10-05 WO disclosed
US-8415400-B2 Synthesizing an amphiphilic block polymer micelle having ionically-charged polymeric segments and nonionically-charged polymeric segments; neutralizing under conditions that allow for self-assembly of polymer micelles; crosslinking; removing the moieties of opposite charge; drug delivery; stability BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2013-04-09 US disclosed
US-8263558-B2 Methods of preparation of recombinant forms of human beta-amyloid protein and uses of these proteins ABBOTT LABORATORIES (US) 2012-09-11 US disclosed
EP-2150820-A1 ANALYSIS METHOD Surescreen Diagnostics Limited (GB) 2010-02-10 EP disclosed
US-20100016392-A1 Pesticidal Aggregates INNOVAFORM TECHNOLOGIES, LLC (US) 2010-01-21 US disclosed
US-20090214515-A1 METHODS OF PREPARATION OF RECOMBINANT FORMS OF HUMAN BETA-AMYLOID PROTEIN AND USES OF THESE PROTEINS ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2009-08-27 US disclosed
EP-2091323-A2 PESTICIDAL AGGREGATES Innovaform Technologies, LLC (US) 2009-08-26 EP disclosed
US-7056532-B1 Compositions for delivery of biological agents and methods for the preparation thereof Univ. Nebraska Bd. of Regents (US) 2006-06-06 US disclosed
EP-1005324-B1 COMPOSITIONS FOR DELIVERY OF BIOLOGICAL AGENTS AND METHODS FOR THE PREPARATION THEREOF UNIV NEBRASKA (US) 2005-03-30 EP disclosed
US-20040228823-A1 Cross-linked ionic core micelles UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 2004-11-18 US disclosed
US-6696089-B2 CROSS-LINKED POLYIONIC POLYMER FRAGMENT AND AT LEAST ONE NONIONIC WATER-SOLUBLE POLYMER FRAGMENT BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2004-02-24 US disclosed
WO-2003082348-A1 NANOGEL NETWORKS INCLUDING POLYION POLYMER FRAGMENTS AND BIOLOGICAL AGENT COMPOSITIONS THEREOF SUPRATEK PHARMA INC. (CA) 2003-10-09 WO disclosed
US-6525058-B1 1-ethyl methylester 4-((3- (p-(carboxyamidino)phenyl) -2-oxo-5-oxazolidinyl)methyl)-1-piperazineacetate; Gantofiban; antagonistic action to Glycoprotein GPIIb/IIIa receptor; oily base; gantofiban citrate YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) 2003-02-25 US disclosed
US-20020136769-A1 Cross-linked polyionic polymer fragment and at least one nonionic water-soluble polymer fragment BOARD OF REGENTS OF THE UNIVERSITYH OF NEBRASKA 2002-09-26 US disclosed
EP-1188440-A1 MEDICINAL COMPOSITION FOR ORAL ADMINISTRATION YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 2002-03-20 EP disclosed
US-6333051-B1 FOR COMBINATORIAL DRUG DELIVERY, OR COMBINATORIAL FORMULATION SUPRATEK PHARMA, INC. (CA) 2001-12-25 US disclosed
WO-1998056348-A1 COMPOSITIONS FOR DELIVERY OF BIOLOGICAL AGENTS AND METHODS FOR THE PREPARATION THEREOF UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 1998-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020136769-A1 Cross-linked polyionic polymer fragment and at least one nonionic water-soluble polymer fragment PUF60, CD44, PCLAF TDP1 2044/4885RECQL 3604/4885PTPN7 1093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.