Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | MB | P02144 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640442 | 0.85 | PDE3B (0.58) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL31173261 | 0.79 | CMA1 (0.59) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL16318310 | 0.79 | CMA1 (0.59) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL10274459 | 0.78 | PDE3B (0.50) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL27780839 | 0.78 | PDE3B (0.46) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL31491338 | 0.78 | CA9 (0.56) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL293858 | 0.78 | MB (0.47) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL3598259 | 0.78 | CA9 (0.56) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL4399001 | 0.75 | PDE3B (0.41) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL16369413 | 0.74 | PDE3B (0.46) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | PDE3B 3066/4885PDE3A 2554/4885CYP11B1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.