Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.60 |
| ▸ | DHODH | Q02127 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131606 | 0.81 | MCL1 (0.65) | SCN9ADHODHMCL1 | |
| SCHEMBL10284484 | 0.78 | SCN9A (0.60) | SCN9AMCL1 | |
| SCHEMBL10284485 | 0.78 | SCN9A (0.60) | SCN9ADHODHMCL1 | |
| SCHEMBL788021 | 0.75 | SCN9A (1.00) | SCN9ADHODHMCL1 | |
| SCHEMBL29421490 | 0.75 | SCN9A (1.00) | SCN9ADHODHMCL1 | |
| SCHEMBL365163 | 0.75 | SCN9A (0.67) | SCN9AMCL1 | |
| SCHEMBL368401 | 0.74 | SCN9A (0.81) | SCN9A | |
| SCHEMBL368520 | 0.74 | SCN9A (0.81) | SCN9A | |
| SCHEMBL368402 | 0.74 | SCN9A (0.81) | SCN9A | |
| SCHEMBL792966 | 0.74 | SCN9A (0.84) | SCN9AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593434-A1 | PYRIDINE COMPOUNDS AS SODIUM CHANNEL BLOCKERS | Purdue Pharma LP (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007836-A1 | PYRIDINE COMPOUNDS AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA .LP. (US) | 2012-01-19 | — | — | WO | disclosed |