SCHEMBL3637680

SCHEMBL3637680

Cc1cc(OCCI)cc(OS(=O)(=O)c2ccccc2Cl)c1

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 20/20 0.69
PRSS2 P07478 6/20 0.67
CTRC Q99895 6/20 0.66
F10 P00742 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3647138 0.94 F2 (0.71) F2PRSS2CTRCF10
SCHEMBL3642918 0.93 F2 (0.70) F2PRSS2CTRCF10
SCHEMBL8158052 0.89 F2 (0.73) F2PRSS2CTRCF10
SCHEMBL27533226 0.88 F2 (0.71) F2PRSS2CTRCF10
SCHEMBL3645053 0.88 F2 (0.54) F2PRSS2CTRCF10
SCHEMBL5674291 0.86 F2 (0.74) F2PRSS2CTRCF10
SCHEMBL6750719 0.85 F2 (0.73) F2PRSS2CTRCF10
SCHEMBL5673452 0.85 F2 (0.69) F2PRSS2CTRCF10
SCHEMBL6553204 0.83 F2 (0.67) F2PRSS2CTRCF10
SCHEMBL7435413 0.82 F2 (0.74) F2PRSS2CTRCF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2178838-A2 NEW THROMBIN FUNCTION COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS BASED ON THEM Obschestvo S Ogranichennoi Otvetsttvennoctiyu "Bionika" (RU) 2010-04-28 EP disclosed
EP-2178839-A2 NEW ANTICOAGULANT COMPOUNDS, PHARMACEUTICAL COMPOSITIONS ON THEIR BASIS TO TREAT THROMBOTIC CONDITIONS, AND PLASMA-SUBSTITUTING SOLUTION TO CORRECT HYPERCOAGULATION DEFECTS OF HEMODILUTION Obschestvo S Ogranichennoi Otvetsttvennoctiyu "Bionika" (RU) 2010-04-28 EP disclosed
WO-2009002228-A2 NEW THROMBIN FUNCTION COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS BASED ON THEM OBSCHESTVO S OGRANICHENNOI OTVETSTTVENNOCTIYU 'BIONIKA' (RU) 2008-12-31 WO disclosed
WO-2009002229-A2 NEW ANTICOAGULANT COMPOUNDS, PHARMACEUTICAL COMPOSITIONS ON THEIR BASIS TO TREAT THROMBOTIC CONDITIONS, AND PLASMA-SUBSTITUTING SOLUTION TO CORRECT HYPERCOAGULATION DEFECTS OF HEMODILUTION OBSCHESTVO S OGRANICHENNOI OTVETSTTVENNOCTIYU 'BIONIKA' (RU) 2008-12-31 WO disclosed