Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3642630 | 1.00 | POLB (0.51) | POLBLTA4HHRH3NOS1 | |
| SCHEMBL10132451 | 0.95 | POLB (0.45) | POLBLTA4HNOS1 | |
| SCHEMBL3644003 | 0.89 | POLB (0.59) | POLBLTA4HHRH3 | |
| SCHEMBL6989999 | 0.84 | POLB (0.51) | POLBLTA4H | |
| SCHEMBL22456087 | 0.84 | POLB (0.51) | POLBNOS1 | |
| SCHEMBL10132466 | 0.84 | POLB (0.51) | POLBNOS1 | |
| SCHEMBL22944146 | 0.78 | POLB (0.48) | POLBLTA4HHRH3NOS1 | |
| SCHEMBL6990304 | 0.77 | POLB (0.66) | POLBLTA4H | |
| SCHEMBL29813025 | 0.77 | POLB (0.66) | POLBLTA4H | |
| SCHEMBL20828207 | 0.77 | POLB (0.66) | POLBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170865-A2 | NOVEL SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF, AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2010-04-07 | — | — | EP | claimed |
| WO-2009010660-A2 | SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF, AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2009-01-22 | — | — | WO | claimed |
| EP-2170865-A2 | NOVEL SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF, AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009010660-A2 | SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF, AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2009-01-22 | — | — | WO | disclosed |