Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 1.00 |
| ▸ | HRH1 | P35367 | 5/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5223012 | 0.98 | HTR2A (0.95) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| SCHEMBL28113806 | 0.86 | HTR2A (1.00) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| SCHEMBL11381572 | 0.85 | HTR2A (0.72) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| Hydrochloric Acid SCHEMBL11389802 | 0.85 | HTR2A (0.96) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| SCHEMBL4811791 | 0.84 | HTR2A (0.70) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| SCHEMBL6900402 | 0.84 | HTR2A (0.70) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| Hydrochloric Acid SCHEMBL29009216 | 0.82 | HTR2A (0.68) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| SCHEMBL19905186 | 0.82 | HTR2A (0.69) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| SCHEMBL2471404 | 0.82 | HTR2A (0.69) | HTR2AHRH1SLC6A4SLC6A2KCNH2 | |
| SCHEMBL14494818 | 0.82 | HTR2A (0.69) | HTR2AHRH1SLC6A4SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920647-A | Novel synthesis process of intermediate side chain alcohol of medicine for treating primary hypertension | 苏州虞美景盛新药开发有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-110563420-B | Construction method of pool | 中地国际工程有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-110563420-A | construction method of pool | 中地国际工程有限公司 | 2019-12-13 | — | — | CN | claimed |
| EP-0743853-B1 | COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES | NPS PHARMA INC (US) | 2001-05-02 | — | — | EP | claimed |
| CN-115677512-A | Method for synthesizing lercanidipine intermediate N-methyl-3,3-diphenylpropylamine hydrochloride | 大连万福制药有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114920647-A | Novel synthesis process of intermediate side chain alcohol of medicine for treating primary hypertension | 苏州虞美景盛新药开发有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114920647-A | Novel synthesis process of intermediate side chain alcohol of medicine for treating primary hypertension | 苏州虞美景盛新药开发有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-110563420-B | Construction method of pool | 中地国际工程有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-110563420-B | Construction method of pool | 中地国际工程有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-110563420-A | construction method of pool | 中地国际工程有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-110563420-A | construction method of pool | 中地国际工程有限公司 | 2019-12-13 | — | — | CN | disclosed |
| EP-3569593-A1 | PRODUCTION OF AMINES VIA A HYDROAMINOMETHYLATION REACTION | Universität Wien (AT) | 2019-11-20 | — | — | EP | disclosed |
| US-4806534-A | SMOOTH MUSCLE RELAXANT, CALCIUM ANTAGONIST | RECORDATI S.A., CHEMICAL & PHARMACEUTICAL COMPANY (CH) | 1989-02-21 | — | — | US | disclosed |
| EP-0299349-A2 | N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-01-18 | — | — | EP | disclosed |
| US-4772621-A | Antihypertensive diphenylpropyl aminopropyl ester of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1988-09-20 | — | — | US | disclosed |
| US-4705797-A | HYPOTENSIVE AGENTS, VASODILATORS | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-11-10 | — | — | US | disclosed |
| EP-0163458-A1 | Tetrahydronaphthalenols for the treatment of hypertension | E.R. Squibb & Sons, Inc. (US) | 1985-12-04 | — | — | EP | disclosed |
| EP-0153016-A2 | Asymmetrical diesters of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1985-08-28 | — | — | EP | disclosed |
| US-4246201-A | Substituted N-(3-phenylthiopropyl)-3,3-diphenyl-propylamines possessing pharmacological activity | ALFA FARMACEUTICI, S.P.A. (IT) | 1981-01-20 | — | — | US | disclosed |
| US-3946063-A | 2,3,4,5,6-PENTAFLUOROBENZYL CHLOROFORMATE | PIERCE CHEMICAL COMPANY (US) | 1976-03-23 | — | — | US | disclosed |